This is totally possible, but a slightly different problem unfortunately. I don’t load or use any SoundEffects in our game; it’s all done through the Wwise API. I suppose they’re both using xAudio though, so perhaps the root cause is the same.
It seems that just by having a reference to the xAudio .dll the problem is created. I’ve tested by only creating the Wwise object in our game and never loading/playing any sounds then letting the game sit idle for 15 minutes before it crashes. I suspect that the fix I posted above in the OP might work, but I don’t know where/how to integrate it with Monogame.